Is there a test for ApoE?
Yes, there is a blood test the can identify whether or not you carry ApoE genes. However, just because you have the gene doesn’t mean that you will or will not develop Alzheimer’s disease. Genetic testing will not predict who diseases will occur in because there are so many other factors — environment and lifestyle are just two — that influence the progression and development of health conditions.
Sure, there’s a test; but unless you’re taking part in a clinical trial and your healthcare provider is trying to diagnose early-onset of Alzheimer’s disease, it isn’t recommended. (Here are the 12 benefits of diagnosing Alzheimer’s disease early.) Testing is used in a research setting so study participants who may have an increased risk of developing Alzheimer’s can be indentify. In this case, scientists can look for how the brain changes and how treatments work. Currently, there isn’t enough information to warrant ApoE testing for all, or necessarily those with a family history of the disease.
Get Involved in Alzheimer’s Research
There are numerous projects that are looking at how genetics affect disease progression, especially as it pertains to Alzheimer’s disease. For these studies to be successful and garner the information needed to fight this disease, volunteers are critical.
To learn more about Alzheimer’s genetics studies, contact National Cell Repository for Alzheimer’s Disease (NCRAD) toll-free at 1-800-526-2839 or visit http://ncrad.iu.edu.
To learn more about volunteering for Alzheimer’s clinical trials and studies, visit www.nia.nih.gov/alzheimers/volunteer.
What to do if you have the gene
Science is just starting to uncover how the ApoE 4 gene influences the development of Alzheimer’s disease. That means it is also unclear what might be done to stop this progression. But there are some insights. For instance, in a February 2016 study published in the Journal of the American Medical Association, researchers found that moderate seafood consumption was correlated with lesser Alzheimer disease neuropathology. There is also some evidence that links too much copper and zinc in the diet to increased risk of Alzheimer’s disease and dementia.
Also, exercise. To find out how physical activity affects your brain, here consider reading:
6 ways physical activity can benefit Alzheimer’s disease
10 ways to decrease your risk of Alzheimer’s disease